Searchable abstracts of presentations at key conferences in endocrinology

ea0086p129 | Reproductive Endocrinology | SFEBES2022

Adipocytes-Derived Extracellular Vesicle-miR-26b Induces the process of Polycystic Ovary Syndrome

Zhou Guannan , Gu Yuanyuan , Zhou Fangyue , Hua Keqin , Ding Jingxin

Background: Adipocyte cells could produce numerous extracellular vesicles and orchestrate the balance of endocrinological system. Polycystic ovary syndrome (PCOS) is a refractory reproductive disease and also a kind of endocrine and metabolic disease. The aim of the study was to explore the effects of adipocyte-derived extracellular vesicles-miR-26b on cumulus cells (CCs) and development of PCOS.Methods: The crosstalk mediated by extracellular vesicle-mi...